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DOH Cardiac Intensive Care Sample Test

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Which of the following diseases/conditions has symptoms of fever, fatigue and weight loss; bleeding gums, nosebleeds, pallor, easy bruising, and petechiae in addition to bone pain?

Correct Answer:

acute leukemia
acute leukemia is a type of cancer that originates in the blood-forming tissues of the bone marrow. it involves the rapid increase of immature blood cells, predominately affecting the white blood cells (leukocytes). this rapid proliferation of cells can interfere with the body's ability to produce healthy blood cells.

the symptoms of acute leukemia can vary significantly but typically include a combination of systemic and specific signs due to the impaired production and function of blood cells. fever, fatigue, and weight loss are common systemic symptoms that occur due to the body's ongoing fight against uncontrolled cell growth and the malfunctioning immune system.

bleeding gums, nosebleeds, pallor (a pale appearance of the skin), easy bruising, and petechiae (small red or purple spots on the body caused by a minor hemorrhage) are symptomatic of the issues related to blood clotting and platelet deficiency. in acute leukemia, the overproduction of abnormal white blood cells can crowd out the production of other types of blood cells, such as platelets, which are crucial for blood clotting. this reduction in platelets leads to the bleeding issues observed.

bone pain, another frequent symptom of acute leukemia, occurs due to the expansion of the bone marrow from the increased proliferation of abnormal cells. this expansion puts pressure on the bones, causing discomfort and pain.

thus, when comparing acute leukemia with other conditions like acute hemorrhage, hodgkin’s lymphoma, and neutropenia, the combination of symptoms such as fever, fatigue, weight loss, bleeding issues, pallor, easy bruising, petechiae, and bone pain most comprehensively points toward acute leukemia. in acute hemorrhage, the primary symptom is rapid and severe blood loss. hodgkin’s lymphoma might share some overlapping symptoms like fatigue and weight loss but is typically characterized by swollen lymph nodes, which is not a primary symptom of acute leukemia. neutropenia, which is an abnormally low count of neutrophils (a type of white blood cell), mainly increases the risk of infections and does not cover the broad range of symptoms seen in acute leukemia.