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Correct Answer: heparin
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*when administering teniposide via intravenous (iv) route, it is crucial to manage the iv line correctly to prevent complications such as precipitate formation. a precipitate can occur when incompatible medications or solutions mix within the iv line, potentially leading to blockages or reduced efficacy of the administered drugs. among the options listed—potassium, dextrose, heparin, and magnesium—the substance known to cause precipitate with teniposide is heparin.
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*heparin, a widely used anticoagulant, can interact with teniposide when both are present in the same iv line. the chemical interaction between teniposide and heparin can lead to the formation of a precipitate. this precipitate not only poses a risk of clogging the iv line but also can interfere with the therapeutic effectiveness of teniposide. as a result, the potential for adverse outcomes in patient care increases.
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*to prevent such issues, it is recommended that the iv line be flushed thoroughly before and after administering teniposide if heparin is also being used. flushing the line with a compatible solution, such as saline, ensures that any residual heparin is cleared from the line before the introduction of teniposide. similarly, flushing after administering teniposide helps to clear any remaining drug from the line before any subsequent use of heparin.
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*in contrast, other substances mentioned such as potassium, dextrose, and magnesium do not typically form precipitates with teniposide under normal conditions. these substances generally have different compatibility profiles with various iv medications, and their interactions are less likely to cause precipitate formation when managed according to standard infusion protocols.
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*it is essential for healthcare providers to be aware of such interactions and to follow recommended guidelines for iv administration to ensure safe and effective patient care. checking for compatibility between drugs and flushing iv lines as recommended are simple yet critical steps in preventing complications such as precipitates during iv therapy.
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