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OAE Biology (007) Practice Tests & Test Prep by Exam Edge

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OAE Biology Sample Test

1 of 5

Two genes are on different chromosomes. Which is closest to the recombination frequency?

Correct Answer:

50%.

the concept of recombination frequency is crucial in understanding the genetic linkage between genes. recombination frequency refers to the percentage of recombinant offspring resulting from crossovers during meiosis, compared to the total offspring. this frequency is directly related to the distance between genes on a chromosome; the closer the genes are, the lower the likelihood of a recombination event occurring between them.

when genes are located on different chromosomes, their assortment into gametes during meiosis is independent. this independent assortment results in a recombination frequency close to 50%, because each combination of alleles has approximately an equal chance of occurring. this situation mimics what occurs when genes are unlinked, meaning they are either far apart on the same chromosome or on different chromosomes.

in contrast, a recombination frequency of 1% indicates that the genes are very close to each other on the same chromosome. in genetic mapping, this is quantified as 1 centimorgan, representing a 1% chance that a crossover will occur between two genes per generation. this implies a strong linkage between the genes, with very low recombination.

a recombination frequency of 100% would theoretically mean that there is always recombination between two genes, indicating complete independence. however, this is practically impossible because even genes on different chromosomes do not always assort independently due to mechanisms like gene linkage and chromosomal arrangements that can affect the outcome.

therefore, when it is stated that two genes are on different chromosomes, a recombination frequency of 50% is most plausible and accurate. this frequency reflects the random assortment of chromosomes during meiosis, leading to an equal probability of inheriting any combination of alleles from the two genes. hence, the correct answer is 50%.