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Correct Answer: jacobsen syndrome.
when considering the genetic conditions listed in the question, the correct answer is jacobsen syndrome. this syndrome is characterized specifically by the absence of genetic material from chromosome 11. let’s explore the conditions mentioned to further understand why jacobsen syndrome is the correct answer:
jacobsen syndrome, also known as 11q deletion disorder, occurs due to a deletion of a segment of chromosome 11. this results in a wide range of developmental and physical abnormalities. individuals with this syndrome may experience delayed development, cognitive impairment, distinctive facial features, and various other health issues. the key factor that identifies this syndrome in the context of the question is the chromosomal deletion on chromosome 11.
kawasaki disease, in contrast, is not caused by a chromosomal deletion but is an acute inflammatory condition that affects the blood vessels throughout the body. it primarily affects children and is not linked to a specific genetic deletion but rather to an autoimmune response. symptoms include fever, rash, swelling of the hands and feet, irritation and redness of the eyes, swollen lymph nodes, and redness of the lips, tongue, or throat.
tar syndrome, or thrombocytopenia-absent radius syndrome, is characterized by the absence of the radius bone in the forearms and a significantly reduced platelet count which leads to bleeding and bruising. this condition is caused by a deletion on chromosome 1, not chromosome 11, which specifically impacts the rbm8a gene.
lastly, wiskott-aldrich syndrome is a genetic disorder that mostly affects males and is due to mutations in the was gene located on the x chromosome. it affects both the immune system and blood cells, leading to symptoms such as easy bruising, bloody diarrhea, episodes of excessive bleeding, and a high susceptibility to infections.
in summary, among the conditions listed, only jacobsen syndrome is associated with the deletion of genetic material from chromosome 11, making it the correct answer to the question. the other conditions are linked to different genetic abnormalities or are not genetic in origin, as in the case of kawasaki disease.
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